Southern Illinois Vacations from $247

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Photo by Southernmost Illinois Tourism Bureau
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Your Southern Illinois Vacation

When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travelers from far and wide. Lake Sara and Effingham Performance Center are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.

The Latest Southern Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

$247
per person
Oct 23 - Oct 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
Would stay there again. No complaints.

Reviewed on Sep 13, 2026

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

$681
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (266 reviews)
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.

Reviewed on Sep 4, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$648
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
The Cheshire

The Cheshire

Save 100% on your flight
$413
per person
Oct 23 - Oct 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,004 reviews)
It was a unique place, nice to have a pub close. Staff was friendly and room was clean. The breakfast had some highs and lows, would have liked to see a little bit more variety for gluten free patrons. Basso next door has great happy hour food and drinks. There is a Starbucks on property also. We were able to Uber everywhere we wanted to go with no issues.

Reviewed on Sep 13, 2026

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

Save 100% on your flight
$616
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
Everything was amazing but the tv you can only watch one channel . So I believe upgrade on the tv every will be great.

Reviewed on Sep 12, 2026

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Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Default Image

Mulberry Hills

While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

A tall water tower with a red and white striped top, surrounded by trees and a clear blue sky.

Uptown

If you're spending some time in Uptown, World's Largest Catsup Bottle and Kruta Bakery are top sights worth seeing.

A river with a bridge, a city skyline, and a large industrial area.

Alorton

Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark.

A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

Stay near popular Southern Illinois attractions

A rocky landscape with a sunset in the background.

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties
A rock formation with a tree growing in the center.
Photo by Southernmost Illinois Tourism Bureau

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
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World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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O'Fallon Family Sports Park

8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
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Harrah's Metropolis

8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
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Southern Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
$106 total
Sep 20 - Sep 21
Total with taxes and fees
9.2/10 Wonderful! (1,023 reviews)
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."

Reviewed on Sep 13, 2026

Drury Inn & Suites St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
$123 total
Sep 20 - Sep 21
Total with taxes and fees
9.8/10 Exceptional! (1,810 reviews)
"The room was clean, the beds were cozy,the food and drinks were excellent, the pool and hot tub was amazing, and the staff was more than friendly! I love the Drury!"

Reviewed on Sep 13, 2026

Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

1409 W US 50 O'Fallon IL
Fully refundable
$67 nightly
$77 total
Oct 5 - Oct 6
Total with taxes and fees
7.4/10 Good! (1,003 reviews)
"Mold on shower curtain and hair on walls, dingy carpet in room and dingy tile in bathroom, noisy upstairs at 5am possibly construction?? For 200$ night, a terrible deal! Breakfast was blah, happy travels!"

Reviewed on Sep 13, 2026

Quality Inn O'Fallon - St. Louis - Shiloh
See all 1,204 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southern Illinois Vacation Packages

Things to do near Southern Illinois

Southern Illinois offers a perfect blend of outdoor adventures and romantic escapes. Visitors can enjoy thrilling ziplines, scenic wine tastings, and extensive hiking trails that showcase the area's natural beauty. With its charming campgrounds and recreational areas, Southern Illinois is ideal for those seeking both excitement and relaxation in a picturesque setting.

Shopping

King City Square Shopping Center, located 5 miles from Southern Illinois, offers a vibrant shopping experience with a mix of entertainment and family-friendly activities. Explore various stores for unique gifts and souvenirs that capture the essence of the region.

Recreation

Experience the vibrant culture at the Benton Civic Center, where entertainment meets romance. Enjoy the serene wellness vibes of Lincoln Park, perfect for relaxation, or visit Waltonville Public Use Area for a peaceful retreat in nature, fostering rejuvenation and tranquility just a short drive away.

Adventure

The I-57 Drag Strip offers thrilling motor racing experiences, located 23 miles from Southern Illinois. Feel the adrenaline rush as cars zoom past, surrounded by a vibrant atmosphere filled with sports enthusiasts. It's an exhilarating spot for anyone looking to embrace high-speed excitement.

Nightlife

Southern Illinois boasts a vibrant nightlife with unique bars and live music venues. Check out the Hangar 9 in Carbondale for great live performances and craft brews. For a relaxed vibe, visit Pheasant Hollow Winery to enjoy local wines and scenic views while unwinding with friends.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and those seeking romantic getaways, offering stunning scenery and adventure. Explore its beautiful lakes, national and state parks, and modern colleges and universities. The area's attractions cater to travelers looking for unforgettable outdoor experiences amidst breathtaking landscapes.

  • Jefferson County Fairgrounds: Located 3 miles from Southern Illinois, the Jefferson County Fairgrounds offers a lively atmosphere perfect for family outings. Experience local culture through seasonal fairs, exhibitions, and events, with plenty of outdoor space for relaxing and enjoying the festivities.
  • Rend Lake: A scenic 13 miles from Southern Illinois, Rend Lake is a picturesque destination ideal for beach lovers and romantics. With its stunning views, outdoor activities, and serene environment, it's perfect for picnics, boating, and sunset strolls along the shore.
  • Veterans Memorial Park: Situated 4 miles from Southern Illinois, this memorial park provides a contemplative space to honor those who served. With its cultural significance and beautiful landscaping, it's an excellent spot for reflection and appreciation of local history.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6000000000000001°C)Light RainMostly CloudySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostly CloudySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnyAverageSlightly High
May66.7°F (19.3°C)Light RainMostly SunnySlightly HighAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnyAverageAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnySlightly LowAverage

Tips to save on your trip to Southern Illinois

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Southern Illinois.
  • Consider traveling during the off-peak season (typically January to February and November) for more affordable package holidays to Southern Illinois.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Southern Illinois Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.