Southern Illinois Vacations from $475

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Photo by Southernmost Illinois Tourism Bureau
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Your Southern Illinois Vacation

When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travelers from far and wide. Lake Sara and Effingham Performance Center are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.

The Latest Southern Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.
Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa

$475
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9/10 Wonderful! (1,003 reviews)
The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$553
per person
Dec 3 - Dec 8
found 10 hours ago
Roundtrip non-stop flight included
New York (JFK) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
Moonrise Hotel

Moonrise Hotel

Delmar Loop
$687
per person
Dec 3 - Dec 8
found 10 hours ago
Roundtrip non-stop flight included
New York (JFK) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Juan the front desk person who checked me and my two babies in at 2 AM was so compassionate and kind.

Reviewed on Sep 16, 2026

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Midtown
$585
per person
Dec 3 - Dec 8
found 10 hours ago
Roundtrip non-stop flight included
New York (JFK) to St. Louis (STL)
7.8/10 Good! (1,002 reviews)
The Cheshire

The Cheshire

$737
per person
Dec 3 - Dec 8
found 10 hours ago
Roundtrip non-stop flight included
New York (JFK) to St. Louis (STL)
8.8/10 Excellent! (1,004 reviews)
Charming and quaint alternative to a Holiday Inn. It was renovated 10-15 years ago but not much care since then. The pool was allegedly open still (mid September) but when we looked out to go use it, there was debris in it and it wasn’t very inviting. The price was affordable and it was pet friendly, I only wish we could have experienced it during its heyday years ago when it was properly maintained and cleaned.

Reviewed on Sep 17, 2026

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Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

A tall water tower with a red and white striped top, surrounded by trees and a clear blue sky.

Uptown

If you're spending some time in Uptown, World's Largest Catsup Bottle and Kruta Bakery are top sights worth seeing.

Default Image

Mulberry Hills

While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

A river with a bridge, a city skyline, and a large industrial area.

Alorton

Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark.

A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

Stay near popular Southern Illinois attractions

A rocky landscape with a sunset in the background.

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties
A rock formation with a tree growing in the center.
Photo by Southernmost Illinois Tourism Bureau

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
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World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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O'Fallon Family Sports Park

8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
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Harrah's Metropolis

8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
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Southern Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$93 nightly
$105 total
Sep 28 - Sep 29
Total with taxes and fees
9.2/10 Wonderful! (1,022 reviews)
"Clean rooms awesome breakfast and staff"

Reviewed on Sep 17, 2026

Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$95 nightly
$114 total
Oct 18 - Oct 19
Total with taxes and fees
Drury Inn & Suites Marion
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
$125 total
Sep 27 - Sep 28
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
See all 1,204 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southern Illinois Vacation Packages

Things to do near Southern Illinois

Southern Illinois offers a perfect blend of outdoor adventures and romantic escapes. Visitors can enjoy thrilling ziplines, scenic wine tastings, and extensive hiking trails that showcase the area's natural beauty. With its charming campgrounds and recreational areas, Southern Illinois is ideal for those seeking both excitement and relaxation in a picturesque setting.

Shopping

King City Square Shopping Center, located 5 miles from Southern Illinois, offers a vibrant shopping experience with a mix of entertainment and family-friendly activities. Explore various stores for unique gifts and souvenirs that capture the essence of the region.

Recreation

Experience the vibrant culture at the Benton Civic Center, where entertainment meets romance. Enjoy the serene wellness vibes of Lincoln Park, perfect for relaxation, or visit Waltonville Public Use Area for a peaceful retreat in nature, fostering rejuvenation and tranquility just a short drive away.

Adventure

The I-57 Drag Strip offers thrilling motor racing experiences, located 23 miles from Southern Illinois. Feel the adrenaline rush as cars zoom past, surrounded by a vibrant atmosphere filled with sports enthusiasts. It's an exhilarating spot for anyone looking to embrace high-speed excitement.

Nightlife

Southern Illinois boasts a vibrant nightlife with unique bars and live music venues. Check out the Hangar 9 in Carbondale for great live performances and craft brews. For a relaxed vibe, visit Pheasant Hollow Winery to enjoy local wines and scenic views while unwinding with friends.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Southern Illinois

Southern Illinois is perfect for outdoor enthusiasts and those seeking romantic getaways, offering stunning scenery and adventure. Explore its beautiful lakes, national and state parks, and modern colleges and universities. The area's attractions cater to travelers looking for unforgettable outdoor experiences amidst breathtaking landscapes.

  • Jefferson County Fairgrounds: Located 3 miles from Southern Illinois, the Jefferson County Fairgrounds offers a lively atmosphere perfect for family outings. Experience local culture through seasonal fairs, exhibitions, and events, with plenty of outdoor space for relaxing and enjoying the festivities.
  • Rend Lake: A scenic 13 miles from Southern Illinois, Rend Lake is a picturesque destination ideal for beach lovers and romantics. With its stunning views, outdoor activities, and serene environment, it's perfect for picnics, boating, and sunset strolls along the shore.
  • Veterans Memorial Park: Situated 4 miles from Southern Illinois, this memorial park provides a contemplative space to honor those who served. With its cultural significance and beautiful landscaping, it's an excellent spot for reflection and appreciation of local history.

Best time to go to Southern Illinois

The best time to visit Southern Illinois is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January30.9°F (-0.6000000000000001°C)Light RainMostly CloudySlightly LowSlightly Low
February36.9°F (2.7°C)Light RainMostly CloudySlightly LowSlightly Low
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April55.2°F (12.9°C)Light RainMostly SunnyAverageSlightly High
May66.7°F (19.3°C)Light RainMostly SunnySlightly HighAverage
June75.9°F (24.4°C)Light RainMostly SunnySlightly HighSlightly High
July78.8°F (26.0°C)Light RainMostly SunnySlightly HighSlightly High
August77.0°F (25.0°C)Light RainMostly SunnyAverageAverage
September71.2°F (21.8°C)Light RainMostly SunnyAverageAverage
October56.7°F (13.7°C)Light RainMostly SunnyAverageAverage
November46.6°F (8.1°C)Light RainMostly SunnyAverageSlightly Low
December39.0°F (3.9°C)Light RainMostly SunnySlightly LowAverage

Tips to save on your trip to Southern Illinois

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Southern Illinois.
  • Consider traveling during the off-peak season (typically January to February and November) for more affordable package holidays to Southern Illinois.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Southern Illinois Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.